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Drug Screening and Confirmation Using Two LC Columns and Identical LC-MS/MS Conditions into a Single, for Streamlined Forensic
Workflow (TN-1369)
This tech note summarizes a harmonized LC-MS/MS method for screening and confirmation of a large panel of 60 drugs and metabolites in urine that was validated to meet the new ANSI/ASB 121 Standard using two Phenomenex HPLC columns and the ToxBox forensic test kits. This more efficient workflow should reduce turnaround time and sample backlogs for drug analysis, compared to traditional immunoassay screening followed by GC-MS confirmation for medicolegal casework.
Drug Screening and Confirmation Using Two LC Columns and Identical LC-MS/MS Conditions into a Single, for Streamlined Forensic Workflow (TN-1369)
This tech note summarizes a harmonized LC-MS/MS method for screening and confirmation of a large panel of 60 drugs and metabolites in urine that was validated to meet the new ANSI/ASB 121 Standard using two Phenomenex HPLC columns and the ToxBox forensic test kits. This more efficient workflow should reduce turnaround time and sample backlogs for drug analysis, compared to traditional immunoassay screening followed by GC-MS confirmation for medicolegal casework.
Document Type:
Technical Notes
Target Industries:
Techniques:
Brands:
Separation Modes:
Reversed Phase
Drug Screening and Confirmation Using Two LC Columns and Identical LC-MS/MS Conditions into a Single, for Streamlined Forensic Workflow (TN-1369)
This tech note summarizes a harmonized LC-MS/MS method for screening and confirmation of a large panel of 60 drugs and metabolites in urine that was validated to meet the new ANSI/ASB 121 Standard using two Phenomenex HPLC columns and the ToxBox forensic test kits. This more efficient workflow should reduce turnaround time and sample backlogs for drug analysis, compared to traditional immunoassay screening followed by GC-MS confirmation for medicolegal casework.
| Target Industries: | Clinical Research, Forensic Toxicology |
| Techniques: | HPLC |
| Brands: | Kinetex |
| Separation Modes: | Reversed Phase |
| Phases: | Kinetex Biphenyl, Kinetex C18, Kinetex Phenyl-Hexyl |
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.